|Magnetic iron oxide nanoparticles solution
Inorganic materials are materials made of silicates, aluminates, borates, phosphates, germanates and other raw materials or oxides, chlorides, carbides, borides, sulfides, silicides, halides and other raw materials prepared by a certain process, which is the general name of all materials except metal materials and polymer materials. Traditionally, inorganic materials refer to materials made of SiO2 and its silicate compounds as the main components, so they are also called silicate materials, mainly ceramics, glass, etc. New inorganic materials are made of oxides, chlorides, carbides, borides, sulfides, silicides and a variety of inorganic non-metallic compounds by a special advanced process of materials. Mainly including new ceramics, special glass, porous materials, etc.
(1) Fe3O4 nanoparticles
In addition to surface effect, quantum size effect and volume effect, it can also present some unique physical properties, such as superparamagnetism, high saturation magnetization strength, biocompatibility, low toxicity, etc. At present, Fe3O4 nanoparticles have wide application prospects in in vivo drug targeting delivery, separation and transfection of DNA, immunoassay, gene vector preparation and medical diagnosis.
Hydroxyapatite (HAP) is the most important inorganic component of human teeth and bones, and synthetic hydroxyapatite is consistent with the calcium salts of natural bone tissue in terms of composition and structure. HAP has received much attention in the fields of drug delivery, bone repair and tissue engineering because of its good biocompatibility, biodegradability and bioactivity.
Their advantages are as follows: good biocompatibility, biodegradability and bioactivity; large specific surface area, uniform pore size and large pore volume, easy to load a large amount of drugs and slow release at a constant rate; hydroxyl groups of HAP can interact with drugs containing hydroxyl groups by hydrogen bonding, increasing the drug loading and improving the drug release characteristics.
(3) Calcium carbonate
Calcium carbonate (CaCO3) is one of the major biominerals, which is widely present not only in living organisms but also in large quantities in nature. CaCO3 has three crystalline structures: calcite, aragonite and spherulite, with calcite being the most stable at room temperature and pressure and spherulite being less thermodynamically stable. CaCO3 microspheres have small volume, large specific surface area and large porosity, and are widely used in biotechnology, pharmaceutical and other high-end industries.