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| Catalog Number: | MSMN-076 |
| Price: | Online Inquiry |
| Category: | Polymers |
| Product Name | COOH-PEG-PLGA |
| Synonym(s) | Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide) |
| Molecular Weight | PEG average Mn 5,000 (by NMR); PLGA average Mn 20,000 (by NMR) |
| Molecular Formula | H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nC2H3O2 |
| Feed Ratio | Lactide:Glycolide 50:50 |
| Form | Powder or Chunks |
| Color | White to Tan |
| Storage Temp. | -20°C |
| Packaging Information | 100 mg |
| Application | Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery. |
| Storage Class Code | 11 - Combustible Solids |
| WGK | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
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